In this study, pEGFP-LUC was used as a model plasmid and three distinct cationic lipids (dioleyloxy-propyl-trimethylammonium chloride [DOTMA], dioleoyl trimethylammonium propane [DOTAP], and cetylpyridinium chloride [CPC]) were tested along with PEG 5000, as a nonionic surfactant, to prepare glyceryl monostearate (GMS)-based cationic solid lipid na
Malignant multiple sclerosis: clinical and demographic prognostic factors
ABSTRACT Patients with Desk malignant multiple sclerosis (MMS) reach a significant level of disability within a short period of time (Expanded Disability Status Scale score of 6 within five years).The clinical profile and progression of the disease were analyzed in a Brazilian cohort of 293 patients.Twenty-five (8,53%) patients were found to have M
A Time-Domain Asymptotic Approach to Predict Saddle-Node and Period Doubling Bifurcations in Pulse Width Modulated Piecewise Linear Systems
In this paper closed-form conditions for predicting the boundary of period-doubling (PD) bifurcation or saddle-node (SN) bifurcation in a class of PWM piecewise linear systems are obtained from a time-domain asymptotic approach.Examples of switched system Desk considered in this study are switching dc-dc power electronics converters, temperature co